ESGLI 2018

Du 28/08/2018 au 30/08/2018

Domaine de Rockefeller - 8 Avenue Rockefeller, 69008 Lyon, FRANCE

Conférenciers invités

Professor Carmen Buchrieser
Institut Pasteur, Paris

Conference title:

Carmen Buchrieser is Professor at the Institut Pasteur, in Paris, France. Her major research interest is to understand how bacteria cause disease: what are the genetic factors conferring bacterial virulence, how do they evolve, what are the mechanisms by which they allow subverting host functions and more generally how do human pathogens emerge. She uses Legionella as a model, as these bacteria are at the crossroad between an environmental bacterium (parasite of protozoa) and a human pathogen (replicating in alveolar macrophages). The projects of her laboratory are focused on the identification and study of virulence factors of Legionella pneumophila and L. longbeachae, with particular emphasis on their functions, their regulation and the mechanisms leading to their acquisition and their evolutionary origin. Recently she developed a new research topic, the study how Legionella is targeting organelles in the host cell. These studies have increased our interest in the analyses of the host response to infection by an intracellular pathogen and to identify he host pathways that are necessary to fight infection.

Alex W. Ensminger, Ph.D.
Assistant Professor - Dept. of Biochemistry, Dept. of Molecular Genetics, University of Toronto

Conference title: "Effect the unexpected: metaeffectors in L. pneumophila and beyond"

Professor Ross Fitzgerald
Molecular Bacteriology, The Roslin Institute, Edinburgh - Scotland

Conference title: "Population genomics of Legionella spp: insights into epidemiology and virulence"

Ross Fitzgerald is currently Director of Edinburgh Infectious Diseases, and Professor of Molecular Bacteriology at The Roslin Institute, University of Edinburgh. A major research focus of his group has been understanding diversity and evolution among natural populations of pathogenic bacteria, particularly staphylococci associated with human and animal infections. In addition, recent studies of Legionella spp have provided insights into the origin of outbreaks and the structure of Legionella populations. In parallel, the function of specific bacterial determinants in the emergence and success of pathogenic clones has been investigated. In addition, a major goal is translation of fundamental discoveries into novel approaches to controlling infectious disease.

Prof. Jacob Moran-Gilad, MD MPH
Ben-Gurion University of the Negev, Beer-Sheva, Israel

Conference title: "A cgMLST scheme for the ESGLI community: Almost there"

Prof. Jacob Moran-Gilad is a Medical Doctor board-certified in clinical microbiology and public health. His main research interest as a Professor of clinical microbiology at the Faculty of Health Sciences, Ben-Gurion University, Beer-Sheva, Israel is development of molecular diagnostics and bioinformatics capabilities for application of genomic approaches in public health microbiology, focusing on water-borne, food-borne and antimicrobial resistant bacteria. He is a Senior Advisor to the Israeli Ministry of Health where he oversees a range of national strategic and policy-making activities and works with stakeholders across government and public sectors. Under this capacity he is leading the National Programme for Legionellosis Control and involved in cross-cutting work relating to emergency preparedness, disease surveillance and outbreak control. Jacob is the Chairperson of the ESCMID Study Group for Genomic and Molecular Diagnostics (ESGMD) and an executive committee member of the ESCMID Study Group for Legionella Infections (ESGLI). Within the ESGLI board, he is responsible for microbiology and NGS and is leading the ESGLI Working Group on WGS for Legionella.

Lara Payne Hallström,
European Centre for Disease Prevention and Control, Solna, Sweden

Conference title: “Epidemiology of Legionnaires’ disease in Europe 2017”

Lara Payne works since over 10 years as an expert and epidemiologist in the Surveillance and Response Support Unit at the European Union agency of the European Centre for Disease Prevention and Control (ECDC). Her daily focus at ECDC is the surveillance activities at EU/EEA level for Legionnaires’ disease through the European Legionnaires’ Disease Surveillance network (ELDSNet). This includes the near real-time surveillance of travel associated Legionnaires’ disease and participating to the response activities of ECDC, such as rapid risk assessments. Prior to ECDC she worked in the national public health agencies of Sweden and the United Kingdom.

Brian Raphael, Ph.D.,
Research Microbiologist, Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Conference title: “Evaluation of a cgMLST scheme for subtyping Legionella pneumophila and comparison with wgMLST”

Brian Raphael currently leads the Legionella laboratory activities within the Pneumonia Surveillance and Response Laboratory in the Respiratory Diseases Branch at CDC. The laboratory is responsible for providing outbreak investigation support, development of new methods for the detection and molecular characterization of Legionella, and conducting applied research into the distribution and diversity of Legionella in the environment. His research activities primarily involve the use of genome sequencing for source attribution of Legionnaires’ disease outbreaks and the development of culture-independent tools for the detection and characterization of Legionella.